Edward N. Siskel (born 1972) is an American lawyer from Chicago who served as the White House Counsel in the administration of U.S. President Joe Biden.

[6] In that role, Siskel oversaw the White House's legal responses to congressional oversight and to complex challenges such as the rollout of the Affordable Care Act.

[8] From 2017 until 2019, he served in the office of corporation counsel for the City of Chicago under Mayor Rahm Emanuel.

[7] From 2019 until he was named White House Counsel, Siskel was chief legal officer for Chicago-based Grosvenor Holdings LLC.

[9] On August 22, 2023, Siskel was named the designate to serve as White House Counsel, replacing Stuart Delery.