[1] His brother Jorge del Barrio was classically trained and moved to Los Angeles, where he worked as an arranger.
Eduardo del Barrio and Jorge Strunz of Costa Rica were the founding members of Caldera, a jazz fusion group.
Caldera was composed of Del Barrio on keyboards, Strunz on guitar, Dean Cortez on bass and Steve Tavaglione on saxophone, Cuban drummer Carlos Vega, and Brazilian percussionist Mike Azevedo.
[9][10] Del Barrio composed "Fantasy", "Runnin' ", "Star",[11] "Sailaway", "Sparkle", "Straight from the Heart" and "Miracles" for Earth, Wind & Fire.
[15][16] Del Barrio collaborated with Dianne Reeves during the recording sessions for Caldera's album Sky Islands when she sang on the song "Ancient Source".
[23][24][25] Del Barrio began his collaboration with Herb Alpert by composing four songs for his 1988 album Under a Spanish Moon.
Del Barrio worked as a composer, orchestrator, and keyboard player on Stan Getz's album Apasionado.