The second season of the Edens Zero anime television series was confirmed through the franchise's official Twitter account on February 9, 2022.

[2] Returning staff include Shinji Ishihira as chief director, Mitsutaka Hirota as script overseer, Yurika Sako as character designer, and Yoshihisa Hirano as music composer.

[3] Based on Hiro Mashima's manga series of the same name, the season season adapts the ninth through sixteenth volumes (chapters 69–140) of the source material, following protagonist Shiki Granbell and the crew of the titular spaceship on their voyage for Mother, the goddess of the cosmos.

The first half of the season focuses on the crew's confrontation with the intergalactic crime lord Drakken Joe, while the second half focuses on the sudden resurrection and betrayal of Shiki's grandfather, the robotic Demon King Ziggy, who wages war on humanity.

[4][7] For the remainder of the season, the opening theme is "Kaibutsu" (械物, a Japanese portmanteau of kai (械, "machine") and kaibutsu (怪物, "monster")) performed by Tani Yuuki, and the ending theme is "My Star" performed by Lozareena.