Edmonton—Spruce Grove was a federal electoral district in Alberta, Canada, that was represented in the House of Commons of Canada from 2004 to 2015.

The suburban portion became part of Sturgeon River—Parkland.

This riding elected the following members of Parliament: Its only Member of Parliament for the duration of the riding's existence was Rona Ambrose, a former columnist and communication consultant, who was first elected to Parliament in the 2004 election as a member of the Conservative Party of Canada.

In the 2004-2005 parliamentary session, she served as a member of the Legislative Committee on Bill C-38, Standing Committee on Finance, Standing Committee on Foreign Affairs and International Trade, and the Subcommittee on Fiscal Imbalance of the Standing Committee on Finance.

Note: Change based on redistributed results.