Her stage, screen and television career lasted from the beginning of the 20th century to 1965.
Beginning in 1915, Holland appeared in silent films, including Always in the Way, The Feud Girl, Mary Moreland and The Masked Rider.
She met her husband on the set of the Masked Rider, a fellow actor named Robert Taber (real name Stuart Fordham Tabor) who was originally from Sag Harbor, Long Island, New York.
After an absence of nearly 20 years and numerous stage roles, Holland resumed making films in the late 1930s.
Middle-aged, she often portrayed "professional women such as teachers, nurses or secretaries" in supporting roles or minor parts.