The self-taught sculptor worked with clay, marble, and bronze from early in his career, and by 1939, had created a number of reliefs as part of a series based on the Adoration of the Magi.

The catacombs underneath Rosario's Teatro El Círculo were then converted into the Eduardo Barnes Museum of Sacred Art in 1940.

Some of the most notable included allegorical sculptures for the Cathedral of Our Lady of the Rosary, bas-reliefs representing the blessing of the Argentine flag and General Manuel Belgrano for the National Flag Memorial (1957), a series of 27 reliefs portraying the Via Crucis for the Church of Saint John the Evangelist (1966), and a monument to the founder of the Bank of Santa Fe, Carlos Casado del Alisal (his best known secular work), in 1970.

[2] The noted sculptor taught in his discipline at numerous Rosario schools, serving as Professor of Drawing at the San Martín National College No.

He purchased a vacation home in Tanti, Córdoba, in which he would spend much of his later years, and adorned the entrance with a work titled La Vestal (modeled after his wife).