Eduardo Simone (born Buenos Aires, 16 October 1974) is an Argentine rugby union footballer.

He started at a very young age playing for his beloved "Liceo Naval", in Buenos Aires, where he eventually got back to finish his career.

Simone had 35 caps for Argentina, from 1996 to 2002, scoring 9 tries, 45 points on aggregate.

He was selected for the 1999 Rugby World Cup finals, playing five matches.

This biographical article relating to Argentine rugby union is a stub.