Edward Ephraim Cross (April 22, 1832 – July 3, 1863) was a newspaperman and an officer in the Union Army during the American Civil War.

In 1854, he canvassed Ohio for the American (Know-Nothing) Party, was the Washington correspondent for the Cincinnati Times during two sessions of Congress, and also wrote articles for other newspapers including the New York Herald.

[1] On July 27, 1858, he left Cincinnati for Tubac, Arizona Territory, with the last contingent of the Santa Rita Silver Mining Company.

In 1860, he crossed the border into Mexico to command a Sonoran army garrison supporting the insurgency of Benito Juárez.

On August 5, 1860, Colonel Cross, assigned to Fort Buchanan, presided a meeting of irate miners, at the ranch of Henry Theodore Titus, who demanded protection from depredations committed by Sonoran bandits.

On July 2, 1863, the division was sent to the left flank to help stabilize it after the Confederates had begun attacking the salient formed by III Corps.

During the Gettysburg campaign, Cross's regiment broke formation so they could move single file over a narrow bridge.