[4] He vigorously defended the past record of his uncle Robert's governments during Queen Anne's reign.
[5] He succeeded his father in 1735 to the Eywood estate at Titley, Herefordshire and his cousin Edward Harley, 2nd Earl of Oxford and Earl Mortimer in 1741 to the earldom and the family seat, Brampton Bryan Hall at Brampton Bryan in Herefordshire.
[3] One of his first acts on succeeding his cousin was to auction off his predecessor's art and coin collection through the auctioneer Cock, at an art sale held under the Piazza, Covent Garden, on 8 March 1741/2 and the five following days, with six more days being required by the coins.
Nearly all the leading men of the day, including Horace Walpole, attended or were represented at this sale, and the prices varied from five shillings for an anonymous bishop's "head" to 165 guineas for van Dyck's group of "Sir Kenelm Digby, lady, and son".
They had several children:[1] Lord Oxford died on 11 April 1755 and was succeeded in his titles by his eldest son Edward.