Edward Henry Knight (1 June 1824, London - 22 January 1883, Bellefontaine, Ohio) was a United States mechanical expert.
He studied surgery, engraving, mechanics, and civil engineering, and emigrated to the United States in 1845.
He settled in Cincinnati, where he became a patent lawyer for several years, and then worked at agricultural pursuits.
In 1863, he accepted a position in the United States Patent Office in Washington, D.C., to work on the preparation of the annual reports.
The meagre reports that were then issued at governmental expense for gratuitous distribution by the Patent Office were replaced by him in 1871 by the Official Gazette of the United States Patent-Office, which was issued as a profitable weekly publication.