Edward La Rue Hamilton (December 9, 1857 – November 2, 1923) was a politician from the U.S. state of Michigan.

Hamilton was born in Niles Township, Michigan, where he attended grade school and graduated from the Niles High School in 1876.

He studied law, was admitted to the bar in 1884, and commenced practice in Niles, Michigan.

Hamilton was elected as a Republican from Michigan's 4th congressional district to the 55th United States Congress and subsequently re-elected to the eleven succeeding Congresses, serving from March 4, 1897 to March 3, 1921.

He engaged in the practice of law until his death in St. Joseph, Michigan in 1923.