The Edward Mooney House is a building at 18 Bowery, at the corner of Pell Street,[3] in the Chinatown neighborhood of Manhattan, New York City.

It was built between 1785 and 1789 for wealthy butcher Edward Mooney on land he purchased after it was confiscated from British Loyalist James De Lancey.

The home was located close to the slaughterhouses, holding pens and tanneries where Mooney made his living; he occupied the house until his death c.1800.

The house would be used as a private residence until the 1820s after which it has served at various times as a hotel, brothel[4] and saloon.

The house was designated a New York City landmark in 1966 and was added to the National Register of Historic Places in 1976.