On 31 December 2016, the quiz made a brief cameo in BBC One’s Peter Pan Goes Wrong TV special.

[2] The new series premiered on 4 October 2021, and alongside a studio change, only four Eggheads and four contestants now played at a time with a reduction to three one-on-one rounds to accommodate advert breaks (due to Channel 5's status as a commercial broadcaster).

Due to social distancing restrictions, the desks were lengthened and perspex screens were added.

The first challengers, playing for charity, were Jay's Virtual Quiz, who had become a fundraising hit on social media during the pandemic.

An additional Egghead (Olav Bjortomt) was featured on the opening credits and competed from week two.

In May 2024, it was revealed that the show has been permanently shelved and Vine said that 'he hasn't filmed an episode for over a year'.

Only once have the Eggheads lost four games in succession and only four times has a team of all five challengers won the final round.

Currently, there are 8 Eggheads (6 male and 2 female): Kevin Ashman, Chris Hughes, Barry Simmons, Pat Gibson, Steve Cooke, Olav Bjortomt, Lisa Thiel and Beth Webster and they currently appear on Channel 5.

It was presented by Jeremy Vine and saw the return of CJ de Mooi, who left Eggheads in 2012.

In each episode, de Mooi faced a team of five contestants hoping to win thousands of pounds.

Lisa Thiel appeared on the show as part of a winning team before becoming an Egghead herself shortly afterwards.

The final round starts out with de Mooi answering ten general knowledge questions.

A 25-part spin-off series ran from 22 August to 23 September 2016, with the search for two new members for the Eggheads line-up: one male, one female.