He played college football for the LSU Tigers and was selected by the Chicago Bears in the second round of the 2014 NFL draft.

A native of Miami, Florida, but raised in Mims, Ferguson originally attended Saint John's Catholic Prep in Frederick, Maryland, before transferring to Hargrave Military Academy in Chatham, Virginia, for his senior year of high school.

Ferguson announced on January 3, 2014 that he would forgo his senior season and enter the 2014 NFL draft.

[10] On November 12, 2015, Ferguson was hit by the NFL with a four-game suspension for violating the league's policy for performance-enhancing drugs.

[11] Ferguson was waived/injured and placed on injured reserve before the start of the 2016 NFL season after sustaining a shoulder injury in the Bears' preseason finale that required season-ending surgery.