Ekavali Khanna made her debut with Kaun Kitne Pani Main, directed by national award winner Nila Madhab Panda in the year 2014.

The same year she worked with another national award-winning director Dr. Chandra Prakash Dwivedi in the film Zed Plus as the parallel lead opposite Adil Hussein.

In 2014 and 2015 she did two more films: Daasdev by Sudhir Mishra and Satra Ko Shaadi Hai, directed by Arshad Sayed.

In 2017 she acted in the Norwegian film What will people say, as Najma she got critically acclaimed globally, the movie directed by Iram Haq was the official entry to the Oscars in 2019.

She also played a pivotal role in Veere Di Wedding, directed by Shashank Ghosh where she stole hearts with her lively Paromita.