It was the first talk show to feature two hosts, with a male ("Él") and female ("Ella") exploring problems that affect average couples and individuals.

[1] Hosts Antonio Farré and Gigi Graciette (replaced by Guillermo Quintanilla and Sofia Webber in 1998) talked about every imaginable topic about problems that affect average couples and individuals, while different panelists and celebrity guests offered their first hand experience on the different subjects.

[2] El y Ella was taped at Raleigh Studios in Los Angeles, California during its early years, sharing its soundstage with fellow talk show, Sevcec.

Midway into its run, El y Ella began taping in Mexico City.

In 1998, both Farré and Graciette left the show for unknown reasons, and were replaced by Guillermo Quintanilla and Sofia Webber, respectively.