From 1999 to 2003, Dijkgraaf was chairperson of the Reformed Political Party Youth, and he ran unsuccessfully for the House of Representatives in the 2006 general election.

[2][3] After a divorce, he entered into a relationship with Tamara van Ark, who is a politician and former Minister for Medical Care for the People's Party for Freedom and Democracy (VVD).

He served on government committees to research the nitrogen crisis in the Netherlands, the future of accountancy, and the effects of a shrinking population on secondary education.

[2] On 20 March 2024 – as part of the 2023–2024 cabinet formation – Dijkgraaf was selected by PVV leader Geert Wilders to serve as informateur alongside Richard van Zwol.

They were tasked with investigating a governing coalition with a concise agreement between the PVV, VVD, NSC, and BBB as recommended by their predecessor Kim Putters within eight weeks.