MacKillop is a single-member electoral district for the South Australian House of Assembly.

It was named in 1991 after Sister Mary MacKillop who served the local area, and later became the first Australian to be canonised as a Roman Catholic saint.

The main population centres are Bordertown, Keith, Kingston SE, Meningie, Millicent, Naracoorte, Penola and Robe.

MacKillop was first contested at the 1993 election, essentially as a reconfigured version of the old electoral district of Victoria.

The last member for Victoria, Dale Baker, a former state leader of the Liberal Party, transferred to MacKillop and won it easily.