[3] Alistar was born on 1 June 1873 in Vaisal commune, at the time in Ismail County, Romania (now in Odesa Oblast, Ukraine).

She was the member of the Moldavian National Party and was elected as an MP from the Cetatea Albă County for the Sfatul Țării.

[8][9] She was one of the two women elected as MP, and actively took part in the political events that led to Bessarabia's unification with Romania.

She was the president of the People's Party, founded by Mareșal Alexandru Averescu, who was also originally from Babele, a commune near Izmail, Budjak which was at the time in the United Principalities of Moldavia and Wallachia and is now in Ukraine.

The newspaper "New Romania" was founded and headed by Onisifor Ghibu, in which have been published many articles signed by Elena Alistar.

After a short stay in Iași, she was arrested by the Communist regime[13] and sent to the town of Pucioasa, then in Ploiești Region [ro] and now in Dâmbovița County, where she died in 1955.