[2][3] Beginning in 2009, she has performed regularly at the Stanislavski and Nemirovich-Danchenko Theatre in Moscow, in roles such as Puccini's Mimì in La bohème and the title role of Madama Butterfly, Tatjana in Tchaikovsky's Eugene Onegin, Leonora in Verdi's La forza del destino,[3][4] Elvira in Mozart's Don Giovanni, Micaela in Bizet's Carmen, Antonia in Offenbach's Les contes d'Hoffmann, Emma in Mussorgsky's Khovanshchina[3][5] and Natasha in Prokofiev's War and Peace.

[2] She appeared as a guest at the Staatstheater Saarbrücken as Jaroslawna in Borodin's Prince Igor[3] and the Deutsche Oper Berlin as Mimi.

She appeared at the Théâtre du Capitole in Toulouse as Gerhilde in Wagner's Die Walküre, at the Theater Basel as Polina in Prokofiev's Der Spieler, the Hamburg State Opera and Opéra National de Lyon, adding roles such as Verdi's Aida and Desdemona, and Puccini's Tosca to her repertoire.

[1] She noted that Dostojevsky, who wrote the novel on which the opera is based, gave the character of Polina many aspects but ultimately left her relationship to the Marquis open, with room for interpretation.

[6] Guseva appeared at the Bavarian State Opera in the 2020/21 season as Liù in Puccini's Turandot and as Marietta in Korngold's Die tote Stadt alongside Klaus Florian Vogt.