Jenkins was selected by the Green Bay Packers with the 44th overall pick in the second round of the 2019 NFL draft.

[5] After entering his rookie season as a backup, Jenkins made his first NFL start on September 22, 2019, in a Week 3 game against the Denver Broncos, replacing an injured Lane Taylor.

[9] Jenkins entered the 2021 season as the Packers starting left tackle in place of an injured David Bakhtiari.

He started eight games there before suffering a torn ACL in Week 11 of a 34–31 loss to the Minnesota Vikings.

[11] On December 23, 2022, Jenkins signed a four-year, $68 million contract extension.