In the main event, Daniel Bryan defeated AJ Styles, Samoa Joe, Kofi Kingston, Randy Orton, and Jeff Hardy in an Elimination Chamber match to retain SmackDown's WWE Championship.

In other prominent matches, Finn Bálor defeated defending champion Bobby Lashley and Lio Rush in a 2-on-1 handicap match to win Raw's Intercontinental Championship, Ronda Rousey defeated Ruby Riott to retain the Raw Women's Championship, and in the opening bout, The Boss 'n' Hug Connection (Bayley and Sasha Banks) defeated Carmella and Naomi, Mandy Rose and Sonya Deville, Nia Jax and Tamina, The IIconics (Billie Kay and Peyton Royce), and The Riott Squad (Liv Morgan and Sarah Logan) in a women's tag team Elimination Chamber match to become the inaugural holders of the WWE Women's Tag Team Championship.

[2] The 2019 event was the ninth Elimination Chamber and took place on February 17, 2019, at the Toyota Center in Houston, Texas.

[10] On the January 14, 2019, episode of Raw, on her segment "A Moment of Bliss", Alexa Bliss unveiled the championship belts and revealed that the inaugural champions would be determined at Elimination Chamber in a tag team Elimination Chamber match, featuring three teams from Raw and SmackDown each, making the championship non-exclusive to either brand.

[11] Qualification matches to determine the three teams from Raw took place on the January 28 and February 4 episodes of Raw: the teams of Nia Jax and Tamina, The Riott Squad (represented by Liv Morgan and Sarah Logan), and The Boss 'n' Hug Connection (Bayley and Sasha Banks) each qualified by defeating the teams of Bliss and Mickie James, Natalya and Dana Brooke, and Alicia Fox and Nikki Cross, respectively.

[12][13] Due to its smaller roster,[14] no qualification matches were held for SmackDown and instead, the teams of Sonya Deville and Mandy Rose, The IIconics (Billie Kay and Peyton Royce), and Naomi and Carmella all announced their participation.

[18][19] At the Royal Rumble, The Miz and Shane McMahon defeated The Bar (Cesaro and Sheamus) to win the SmackDown Tag Team Championship.

[15] At the Royal Rumble, Daniel Bryan defeated AJ Styles to retain the WWE Championship with help from the returning Rowan.

Styles then confronted Bryan and Rowan, followed by Randy Orton, Samoa Joe, Jeff Hardy, and Mustafa Ali.

After an ensuing brawl, WWE Chief Operating Officer Triple H scheduled Bryan to defend the championship against the five in an Elimination Chamber match at the pay-per-view.

[21] Due to a legitimate injury, however, Ali was pulled from the match and replaced with The New Day's Kofi Kingston.

In a backstage interview, Riott stated that she was ensuring that her teammates were okay and claimed that she could defeat Rousey at any time.

[23] On the Royal Rumble Kickoff pre-show, Buddy Murphy defeated Kalisto, Akira Tozawa, and Hideo Itami in a fatal four-way match to retain the WWE Cruiserweight Championship.

[27] During the Elimination Chamber Kickoff pre-show, Buddy Murphy defended the WWE Cruiserweight Championship against Akira Tozawa.

The Boss 'n' Hug Connection (Bayley and Sasha Banks) and Mandy Rose and Sonya Deville started first due to a pre-match stipulation.

The last to enter were Nia Jax and Tamina, who performed stereo Samoan drops on Kay and Royce to eliminate The IIconics.

[29] After that, Bobby Lashley defended Raw's Intercontinental Championship in a handicap match in which he teamed with Lio Rush to face Finn Bálor.

In the end, Bálor performed a "Coup de Gráce" on Rush to win Lashley's title.

[29] In the main event, Daniel Bryan defended SmackDown's WWE Championship in an Elimination Chamber match against Kofi Kingston, AJ Styles, Jeff Hardy, Randy Orton, and Samoa Joe.

[30] On the following episode of SmackDown, a six-man tag team match was scheduled pitting WWE Champion Daniel Bryan, Samoa Joe, and Randy Orton against Kofi Kingston, AJ Styles, and Jeff Hardy.

[32] In a backstage segment, SmackDown Women's Champion Asuka was interrupted by Sonya Deville and Mandy Rose.

[32] Flair then reiterated Triple H's statement from the night before on Raw,[30] saying that Lynch would be arrested the next time she broke her suspension.

[32] On the following episode of 205 Live, General Manager Drake Maverick scheduled a tournament to determine WWE Cruiserweight Champion Buddy Murphy's opponent at WrestleMania 35.