Elisa Cusma (born 24 July 1981 in Bologna) is a former Italian middle-distance runner who specialized in the 800 metres.

She finished seventh at the 2007 World Athletics Final, sixth at the 2008 World Indoor Championships, sixth at the 2008 World Athletics Final and won the bronze medal at the 2009 European Indoor Championships.

She set a personal best time of 1:58.63 at the 2007 World Championships in Osaka.

She also has a personal best time of 4:09.34 in the 1500 metres, achieved in June 2007 in Milan.

Elisa Cusma has won the individual national championship 18 times.