She is also noted as the only woman ever to serve as a partner and take an active leadership role (1790–1800) at Berenberg Bank since the company was established in 1590 by her family.

She however retained a large account with the Berenberg company of several hundred thousand Mark Banco until her death.

Her grandson Hermann Gossler (1802–1877) became First Mayor and President of the Senate (head of state), whereas her great-grandson, Baron Johann von Berenberg-Gossler, was granted the name Berenberg-Gossler by the Senate of Hamburg in 1880, and subsequently ennobled by Prussia in 1888 and raised to baronial rank in 1910.

Percy Ernst Schramm describes her as "a Maria Theresia in miniature" and "a practical woman, who until the end governed her family with undiminished vitality."

Her daughter Anna Henriette Gossler, married Seyler, once wrote that "we all love and revere her indescribably; she also deserves it entirely, because she only lives for her children.