[1] In February 2018, Hughes made her first team debut for Everton in a 1–0 loss against Arsenal at 16 years old.

[1] Hughes scored her first professional goal in a derby win against Liverpool during the group stage of the FA WSL Cup.

[2] On 4 January 2020, Hughes joined Bristol City on loan for the rest of the season.

[4] In 2023-24, Hughes scored 16 goals in 21 games for Crystal Palace, winning the Championship Golden Boot as Palace won promotion to the WSL,[5] however she suffered another ACL injury playing against Lewes in the penultimate game of the season.

[6] Hughes has made appearances for the Wales women's national football team at the under-16 and under-17 levels.