On April 21, 1893, the Pennsylvania Railroad's elevated structure that grade separated the line through Elizabeth opened for service.

[6] On June 9, 1968 the funeral train of Robert F. Kennedy heading south to Washington, DC passed through the station, where crowds lined the tracks to bid farewell and pay tribute.

Prior to its passing, two persons were killed and 5 injured after being struck by a northbound Penn Central train that had originated in Chicago.

[9][10] In January 2015 it was announced that a new station house, platforms, and stairways would be built, a project estimated to cost $55 million (2015 USD).

[11] The design was made in coordination with Amtrak (which owns the NEC but ended Elizabeth stops about 1973) which plans to add a fifth track.