[1] Although she works in a variety of different disease areas, most research focuses on developing better medicines for the treatment and eradication of malaria.

At Stanford she played a leading role in developing seminal post-genome analysis methods in Saccharomyces cerevisiae.

[4][5] In 1999, Winzeler was recruited by Peter G. Schultz to the newly established Genomics Institute of the Novartis Research Foundation.

In 2012, she moved to the University of California, San Diego where she is currently a professor in the Department of Pediatrics and director of Translational Research at the UCSD Health Sciences Center for Immunity, Infection, and Inflammation.

[5] After establishing her own lab, she began applying the powerful, high throughput methods that worked well in yeast to organisms that were both more medically relevant and experimentally-challenging, namely the protozoan Plasmodium parasites that cause human malaria.