According to her Fox Business bio, MacDonald covered the IRS, corporate accounting scandals, taxes and Wall Street for The Wall Street Journal and Forbes Magazine, where she created Forbes' annual ranking, The World's 100 Most Powerful Women.
MacDonald broke stories detailing the Church of Scientology's secret settlement with the IRS and the Kennedys' use of the IRS to target and audit political enemies, as well as thousands of groups and individuals, including Fair Play for Cuba Committee, connected to assassin Lee Harvey Oswald.
MacDonald has also appeared as a guest on NBC's The Today Show, ABC's World News Tonight, Outnumbered, ABC's Nightline, Your World with Neil Cavuto, "On the Record with Greta Van Susteren", "The O'Reilly Factor, CBS This Morning, CNBC's Kudlow & Company with Larry Kudlow, C-SPAN, Court TV, as well as radio shows such as ABC News Radio, and NPR.
Fox News' Neil Cavuto and CNBC's Larry Kudlow have called MacDonald "a true class act" and an "independent voice" in journalism.
MacDonald has argued on camera her support for same-sex marriage and over-the-counter birth control.