She is best known for combining computer graphics, sculpture, and photography to visualize subject matter that includes architecture, historical events, and scientific phenomena such as the AIDS virus, Neutrinos, Microglia, and CRISPR.

[10] Sandor's work has been commissioned by the Jet Propulsion Laboratory, the Smithsonian Institution, and the Tech Museum of Innovation, among others.

[11] Sandor and (art)n have worked with a variety of artists including Ed Paschke,[2] Karl Wirsum, Chris Landreth, Martyl Langsdorf, Donna Cox, Miroslaw Rogala and Claudia Hart.

[13] She is co-editor and contributor to New Media Futures: The Rise of Women in the Digital Arts (2018) published by the University of Illinois Press.

[17] The Richard and Ellen Sandor Family Collection contains photographs, paintings, drawings, sculptures, and new media works focusing around themes such as 19th- and 20th-century icons, Paris between the wars, the American West, Hollywood portraits, and surrealism.