Starting his sophomore year, Panicco became a four-year starter for the 49ers program, amassing a total of 77 appearances for the team, as well as earning one assist during his college career.

Panicco made his college soccer debut on August 29, 2016, in a 6–0 victory against Hofstra, where he would record his first career shutout, and make four saves during the match.

On September 17, 2016, during a conference slate against Old Dominion, Panicco would register his first, and only, collegiate assist, helping Charlotte prevail to a 2–0 victory.

[2] In 2017, in his second year, Panicco helped Charlotte reach the championship match of the 2017 Conference USA Men's Soccer Tournament, where they ultimately lost to Old Dominion.

[7] Pannico was loaned to USL Championship side Austin Bold on May 6, 2021,[8] alongside Nashville SC teammate Nick Hinds.