It is located in an ornate manor at 2200 Massachusetts Avenue, NW on Embassy Row.

It was also formerly accredited to Canada, until the opening of the resident Luxembourgish embassy in Ottawa in late 2024.

[2] The building was originally constructed for lumber baron and former Congressman Alexander Stewart in 1909.

It was designed by Jules Henri de Sibour and built in the French style of Louis XIV.

In 1941, her daughter sold it to Grand Duchess Charlotte of Luxembourg who was then in exile due to the German occupation of her country in the Second World War.