[1] The embassy also operates Consulates-General in Los Angeles, San Francisco, Houston, New Orleans, Miami, and New York City.

The embassy operates several services and offices, responsible for different areas of policy and liaising with the relevant American bodies, the most notable of whom are listed below.

It is responsible for coordination with the American government on matters, particularly foreign policy, that affect Nicaragua, however, the majority of the diplomacy is conducted by the ambassador, leaving the chancery to liaise with the Nicaraguan government and coordinate with the Press Service in matters of public policy.

The office also monitors American press coverage of issues pertaining to Nicaragua and reports back to the ambassador and to Managua.

The duties of the service include promoting Nicaraguan creative works in cultural and academic institutions across Nicaragua, with the help of the attaches in regional consulates.