Occupied since 1978, it is located on 6/8 Karmanitskiy Lane (Russian: Карманицкий переулок, 6/8) in the Arbat District of central Moscow, a short walk from the headquarters of the Russian Ministry of Foreign Affairs, and near the former home of Alexander Pushkin on Arbat Street and the Spaso House, the official residence of the Ambassador of the United States to Russia.

[1] Its first diplomatic mission in Moscow was opened on August 2, 1977, when Juan A. Ona, appointed to serve as the first minister-counsellor to the Soviet Union, operating from Room 786 of the Hotel Ukraina (today the Radisson Royal Hotel, Moscow) on Kutuzovsky Prospekt.

[3] Ona was later joined by two officers to help run the post, becoming the mission's erstwhile chargé d'affaires, and on September 30, 1977, Luis Moreno Salcedo arrived in Moscow as the first resident Philippine ambassador to the Soviet Union.

Today, the building houses both the mission's chancery and the ambassador's official residence.

[2] Upon the dissolution of the Soviet Union in 1991, the Philippine Embassy in Moscow subsequently was accredited to Russia and eleven former Soviet republics, with jurisdiction over Estonia, Latvia, and Lithuania being transferred to the Philippine Embassy in Stockholm, and jurisdiction over Moldova being transferred to the Philippine Embassy in Bucharest.