[3] She has supported and been involved in charity and activism, including the Make-A-Wish Foundation, Mattel Children's Hospital, Time's Up, and the March for Our Lives.

[2][3] In 2010, Skinner starred as one of the leads in short film Sodales, directed by Jessica Biel, which was a part of Glamour Magazine's "Reel Moments".

She has also had several guest roles on television shows including Shake it Up, Days of Our Lives, CSI: Crime Scene Investigation, Austin & Ally, The Mindy Project, Sam & Cat, Criminal Minds, Rizzoli & Isles, and more.

[5] Skinner landed her first major role as Amber on the Disney Channel series Andi Mack, which premiered in 2017.

She auditioned for the roles of Andi, Buffy, and Amber, and participated in a chemistry read with Peyton Elizabeth Lee and Asher Angel.