[2] Beginning her career in 1987 on the British stage, Chambers first drew critical attention for her portrayals of teenage characters in the world premieres of two plays by Alan Ayckbourn at the Stephen Joseph Theatre in Scarborough: Geain in Henceforward... (1987) and Lucy Baines in Invisible Friends (1989).

[7] Chambers began her career as a stage actress in the late 1980s as a member of the repertory company at the Stephen Joseph Theatre in Scarborough.

[9] One of her other early stage appearances was in the role of Tillie in the world premiere of Paul Doust's If I Knew You Were Coming I'd Have Baked A Cake in May 1988 at The Old Red Lion, Islington.

[13] She remained with the latter production when it moved to the Royal National Theatre in 1991; earning positive critical attention for her portrayal of a teenager who engages with an imaginary friend to escape her troubled home life.

[14] In the autumn of 1991 Chambers was a member of Mark Brickman's repertory company at the Crucible Theatre in Sheffield, South Yorkshire where one of her roles was Celia in William Shakespeare's As You Like It.

[15] She returned to the Royal National Theatre in 1993 as Avonia Bunn in Arthur Wing Pinero's Trelawny of the 'Wells' under the direction of John Caird.

[23] At the age of 43, Chambers essentially withdrew from public life after making her final acting appearance in a 2007 special Comic Relief episode of The Vicar of Dibley.