[1] Hamilton made her television debut in the hit Showtime drama series The Tudors, portraying the sharp-tongued Anne Stanhope in seasons three and four.
Notable feature films include the black comedy Whole Lotta Sole with Brendan Fraser by Oscar-winning director Terry George,[5][6] and the action thriller The Cold Light of Day where she starred alongside Bruce Willis and Henry Cavill.
[7][8][9] Hamilton won her first professional role in HBO's World War II film Into the Storm, produced by Ridley Scott, upon graduating drama school.
[10][11] Her first major stage role followed in 2008 in the Royal Exchange Theatre's production of Tennessee Williams' The Glass Menagerie where she played Laura Wingfield opposite Brenda Blethyn, her portrayal described as "a haunting, heartbreaking performance".
[29][30][31][32] Richard II broke records as the fastest selling production in RSC history[33] and when screened live to cinemas around the UK on 13 November 2013, played to an audience of over 60,000.