Hewitt was the lead singer of the Australian rock band Missing Hours, with whom she released an eponymous debut album in October 2008 through Sony Australia.

[5] The single spent a total of 50 weeks in the Billboard Hot Dance Airplay charts in the United States and reached number 1 in December 2007.

In Armin van Buuren's radio show A State of Trance the single was elected by the audience with 2,109 votes as the second best song of the year 2009.

Since then, she has had various collaborations with DJs such as Armin van Buuren, Cosmic Gate, Gareth Emery, Aly & Fila, Dash Berlin, 3lau, Schiller, and Andrew Rayel, which have been placed in Trance charts around the world.

[8] In 2020, Emma Hewitt joined forces with Ilan Bluestone and Maor Levi, forming the progressive trance supergroup Elysian and announcing her debut on the Anjunabeats music label.