During World War II, he was the internationally recognized Prime Minister of Greece from 1941 to 1944 as head of the Greek government in exile.

[1] Emmanuel Tsouderos was born in 1882 in Rethymno, Crete (then part of the Ottoman Empire).

[4] As the evacuation of the Greek government to Crete was being prepared, Tsouderos, as a Venizelist and Cretan, as well as a known Anglophile, emerged as a prominent choice for the post during the 20th.

Following the Greek Civil War, Tsouderos would go on to lead the Democratic Progressive Party (Dimokratikon Proodefitikon Komma).

[8] During the 1950 Election, Tsouderos formed a coalition government with Nikolaos Plastiras' Progressive Liberal Center Party (Komma Proodefitkon Fileleftheron Kentrou),[8] to form the National Progressive Center Union (Ethniki Proodetiki Enosis Kentrou) After the end of World War II Tsouderos served in different capacities, until his death at the age of 73 in Nervi, Genoa, Italy on 10 February 1956.