Emmanuel Rodríguez Vázquez (born August 8, 1992) is a Puerto Rican professional boxer who has held the International Boxing Federation (IBF) bantamweight title twice between 2018 and 2024.

Rodríguez is originally from Urbanización Villa Real near Ojo de Agua, a middle class urban sector of Vega Baja, Puerto Rico.

By 2006, Rodríguez was already competing at a national Youth level, participating in the Juegos Nacionales Escolares 2006, where he defeated Emmanuel Ramírez of Arecibo (2:1) in the 13–14 years (41 kg) division.

[5] As an amateur, his corner team is led by Arturo Ríos and Orlando Rodríguez Zayas, who trained Puerto Rico's previous Olympic medalist, Daniel Santos.

[7] He had previously entered the 2009 Torneo Nacional de Boxeo Aficionado Isaac Barrientos, Puerto Rico's senior national championships, advancing to the semifinals before losing to Waldemar Pagán (12:9).

[9] In the semifinals he fought Bryan Aquino, who had defeated Pagán for Puerto Rico's National Light Flyweight Championship, winning by points (19:5).

[9] On July 5, 2009, Rodríguez competed in the finals of the Copa Olímpica Juan Evangelista Venegas, an annual tournament held by the COPUR, defeating Ángel Acosta by RSC in two rounds.

[10] After ascending to the flyweight division, Rodríguez participated in the Copa Internacional de Boxeo Aficionado San Juan Bautista, a boxing dual where foreign golden gloves winners were invited.

[11] He was expected to compete in the 2010 Torneo Nacional de Boxeo Aficionado Isaac Barrientos, but he was unable to attend, awarding a walkover victory to his scheduled opponent, Jesús Soler.

Rodríguez competed twice, defeating Mexican National Flyweight Champion, Elías Emigdio, (8:6) and fellow Puerto Rican José Núñez (4:0).

At the 2010 Youth World Amateur Boxing Championships which were held in Baku, Azerbaijan, he debuted with a RSC victory over Lassana Camara of Mali, after receiving a bye in the first date of eliminatories.

This was due to recommendations made by the amateur boxing federation and High Performance Department, who wanted Rodríguez to have an uninterrupted preparation for the upcoming event.

[26] Subsequently, a request for inclusion in the High Performance Full-Time Athlete Program was sent to the government, citing an exception to the standard rule, which was drafted to include medalists at the Pan American Games, World Championships or senior Olympics.

[32] In his first interview since the incident, Rodríguez noted that he intended to focus on his career and education from that point onwards, severing ties with any negative influence.

[33] Upon being released, the original plan was to participate in the qualification of the 2011 Pan American Games, but he received a negative report from Enrique Amy, chief doctor of the COPUR's Anti-Doping Commission.

Consequently, Rodríguez spent several months of additional recovery, focused on treatment to avoid re-injuring or infecting the scar tissue in his left arm.

On September 14, 2011, Rodríguez made his official in-ring return at the V Copa Ángel "Cholo" Espada, competing within the super flyweight division.

Rodríguez then entered the Copa Independencia in the Dominican Republic, but lost his fight against Eddie Valenzuela due to injury (RSCI) in the third round.

Rodríguez turned pro on June 1, 2012, in the undercard of a Puerto Rico Best Boxing event, in which he defeated Jason Agosto by knockout in the first round.

[42] Rodríguez faced Miguel Cartagena for the vacant WBO Latino bantamweight title on October 18, 2014, at the Cosme Beitia Sálamo Coliseum in Cataño, Puerto Rico.

[43] Rodríguez made the first defense of his secondary WBO title against Gábor Molnár on February 21, 2015, at the Francisco Deyda Coliseum in Hatillo, Puerto Rico.

[44] Rodríguez made his second title defense against Luis Hinojosa on May 30, 2015, at the Cosme Beitia Sálamo Coliseum in Cataño, Puerto Rico.

[46] Rodríguez faced Alex Rangel for the vacant WBA Fedelatin and WBC interim Latino bantamweight titles on August 22, 2015.

[52] Rodríguez took part in the second season of the World Boxing Super Series, the quarterfinals of which took place in October 2018 and November 2019, and focused on the bantamweight division.

He faced the IBF mandatory bantamweight title challenger Jason Moloney in the tournament quarterfinals, which were held on October 20, 2018, at the Addition Financial Arena in Orlando, Florida.

[57] Rodríguez faced Reymart Gaballo for the vacant WBC interim bantamweight title, with the winner of the bout being expected to challenge the reigning world titleholder Nonito Donaire in the future.

[67] Rodríguez faced the undefeated Gary Antonio Russell on August 14, 2021, at the Dignity Health Sports Park in Carson, California.

[71] Rodríguez faced the one-time WBC International and FECARBOX title challenger Roberto Sanchez Cantu on March 25, 2022, in the main event of the "Estilo Mexicano Box" card which took place at the Polideportivo Juan S. Millan in Culiacán, Mexico.

The bout was scheduled for the undercard of the Deontay Wilder and Robert Helenius Fox Sports pay per view and was a rematch of their August 14, 2021 meeting, which ended in a no contest after just 16 seconds.

[76] The order was abandoned on February 28, as Astrolabio chose to pursue a fight with Jason Moloney for the vacant WBO bantamweight championship.