Ena is located in the Tōnō region of southeastern Gifu Prefecture.

[2] Per Japanese census data,[4] the population of Ena has declined over the past 40 years.

During the post-Meiji restoration cadastral reforms, the area was organised into Ena District, Gifu.

The city was founded on April 1, 1954, by the merger of two towns (Oi and Osashima) and six villages (Tōnō, Sango, Takenami, Kasagi, Nakano, and Iiji), all from Ena District.

Ena has a mayor-council form of government with a directly elected mayor and a unicameral city legislature of 18 members.