Endicott is a village in Jefferson County, Nebraska, United States.

[3] Endicott was platted in 1880 at the junction of the St. Joseph and Western and Chicago, Burlington and Quincy Railroads.

[5][6] It was named for William Crowninshield Endicott, the United States Secretary of War in the Administration of President Grover Cleveland.

[7][8] The Endicott family were stockholders in the Chicago, Burlington and Quincy Railroad.

29.5% of all households were made up of individuals, and 13.1% had someone living alone who was 65 years of age or older.

There were 2.4% of families and 1.6% of the population living below the poverty line, including no under eighteens and none of those over 64.