Other non-infectious causes include toxins, allergic reactions, and retained intraocular foreign bodies.

Endophthalmitis requires immediate medical attention to ensure the condition is diagnosed as soon as possible and treatment is started in order to reduce the risk of the person losing vision in the eye.

Symptoms of endophthalmitis include severe eye pain, vision loss, and intense redness of the conjunctiva.

[3] In both endogenous and exogenous types of endophthalmitis, approximately 20% of people will experience severe vision loss.

[3] A recent systematic review found that the most common source of infectious transmission following cataract surgery was attributed to a contaminated intaocular solution (i.e. irrigation solution, viscoelastic, or diluted antibiotic), although there is a large diversity of exogenous microorganisms that can travel via various routes including the operating room environment, phacoemulsifcation machine, surgical instruments, topical anesthetics, intraocular lens, autoclave solution, and cotton wool swabs.

[3] Fungal sources of endogenous endophthalmitis are usually seen in those who are immunocompromised, with IV drug use and central venous catheter also being important risk factors.

Perioperative antibiotic injections into the eye, specifically cefuroxime at the end of surgery, lowers the chance of endophthalmitis.

[11] There is evidence to suggest that a solution of povidone-iodine and antibiotics applied pre-injection may be effective at preventing some cases of endophthalmitis in people undergoing intravitreal injections.

[12] Intravenous antibiotics given prophylactically in those with penetrating eye trauma has shown a reduction in the incidence of exogenous endophthalmitis.