The first season of the drama television series created by Hubert Barrero Enemigo íntimo premiered on Telemundo on 21 February 2018, at 10.00 pm in the U.S., and concluded on 7 May 2018.

[1][2] It consists of fifty-three episodes, each of approximately 45 minutes.

Enemigo íntimo features a large ensemble cast, including Raúl Méndez, Fernanda Castillo, Matías Novoa, Rafael Sánchez Navarro, Guillermo Quintanilla, Leonardo Daniel, and Otto Sirgo in the starring roles.