Since 2018 it has been part of UK Research and Innovation, which is funded through the Department for Business, Energy and Industrial Strategy.

From 2007 to March 2014, the chief executive and deputy chair of EPSRC was David Delpy, a medical physicist and formerly vice provost at University College London.

[5] In April 2016 Professor Tom Rodden was appointed as the Deputy CEO of EPSRC, a new position created to work alongside Philip Nelson while he also acts as Chair of RCUK Strategic Executive.

Rodden joins the EPSRC on secondment from the University of Nottingham where he is currently Professor of Computing and Co-Director of Horizon Digital Economy Research.

[10] In 2020, ESPRC received £22 million from UKRI to be used (alongside money from industry and the universities involved) to fund five "next stage digital economy" centres.