Counties within (or partially within) its circulation area include Alfalfa, Blaine, Garfield, Grant, Kingfisher, Logan, Major, Noble, Woods, and Woodward.
This ultimately led to a showdown between Isenberg and R. W. Patterson, Registrar of the United States Land Office.
Isenberg had expected preferential treatment concerning the purchases of advertisements, as they were both Democrats, but Patterson instead favored a competing newspaper at the time, the Tribune-Democrat.
Former Enid Mayor and Oklahoma Congressman Milton C. Garber served as editor and president.
William M. Taylor, vice president and business manager, owned the paper along with Will and Edmund Frantz.
Hollinger sold off most of its small papers in 1999, the Enid News & Eagle went to Community Newspaper Holdings.