The Enjoy Illinois 300 (currently known for sponsorship reasons as the Enjoy Illinois 300 presented by TicketSmarter) is a NASCAR Cup Series race at World Wide Technology Raceway (formerly Gateway Motorsports Park) in Madison, Illinois in the Greater St. Louis metropolitan area, first held in 2022.

A NASCAR Camping World Truck Series race, the Toyota 200 presented by CK Power, which was previously a standalone race on the series' schedule before the track received a Cup Series date, is held on the same weekend as this race.

On August 21, 2021, Adam Stern from Sports Business Journal reported that NASCAR was in talks to have the track host a Cup Series race in 2022.

[1] On September 8, he reported that Gateway would be on the 2022 Cup Series schedule and would replace one of the two races at Pocono Raceway.

[4] The stage lengths for the race were confirmed to be 45-95-100 laps for the Cup Series.