Beginning at the parking lot for the Piper-Cox Museum, the Buckquarter Creek Trail goes up the river at Few's Ford.

The 3.75-mile (6.04 km) trail passes a picnic area and crosses the suspension foot bridge.

Fanny's Ford Trail is a 1.01-mile (1.63 km) loop and is mostly made up of flat ground and gentle hills.

The larger eastern loop follows the river bank for almost a mile, before climbing a 250-foot (76 m) rise in elevation.

It is 2.49 miles (4.01 km) long and generally stays close to the river except for short sections where cliffs and bluffs force it up and around on ridges.

It begins at the Nancy Rhodes Creek bridge on Rivermont Road and makes a 1.5 miles (2.4 km) loop.

The foundations of Durham’s first water pumping station are near the river at the northeast section of the loop.

Native Americans of the Eno, Shakori and Occoneechee tribes lived along the river prior to European settlement.

[4] Margaret Nygard, a British resident of the area, rallied concerned citizens to campaign and save the Eno.

The Eno River Association was established in 1966 and played an important role in creating the park.

As a part of its conservation role the group engages in public outreach, notably producing the annual Festival for the Eno.