He also worked to defend the lives of the Jewish people during World War II and contributed to DELASEM.

During World War II he made his support of the Jewish people known and was quite vocal of the injustices against them during the Holocaust that Nazi Germany was perpetrating; due to this he collaborated with DELASEM and was even arrested on 8 December 1943 though released with strong threats and warnings.

[1] With Pope John XXIII introducing the Second Vatican Council, Bartoletti was known for his remarkable contribution to catechetical and liturgical reform.

Pope Paul VI appointed him as the Secretary General of the Italian Bishop's Conference in 1972; he possessed great political tact in realizing and addressing the potential consequences of a referendum on divorce.

The title Servant of God was bestowed upon Bartoletti on 4 September 2007 after the Congregation for the Causes of Saints - under Pope Benedict XVI - granted their approval to the beginning of the process.