Enrique Patricio Cáceres Villafañe (Spanish pronunciation: [enˈrike paˈtɾisjo ˈkaseɾes βiʎaˈfaɲe]); born 20 March 1974) is an international football referee from Paraguay.

He refereed his first international match, a friendly between Cuba and Bolivia, in 2012 where he awarded four yellow cards and one red[3][4] Cáceres has also refereed matches in FIFA Club World Cup and FIFA U-20 World Cup at the international level.

During the international matches, he is assisted by countrymen Eduardo Cardozo and Juan Zorrilla.

Cáceres regularly referees matches in the Paraguayan Primera División.

[5] First appointed to the FIFA Referees Commission in 2021, Cáceres remains a representative as of August 2024.