It had jurisdiction over regions of Slovakia (Slovak: Slovensko) and Subcarpathian Rusynia (Rusyn: Підкарпатьска Русь), at that time parts of former Czechoslovakia.
After the Hungarian conquest of the region and the acceptance of Roman Catholicism as official form of Christianity in the medieval Kingdom of Hungary, Eastern Orthodoxy was gradually suppressed.
Ecclesiastical order of Eastern Orthodox Church in the region was later revived under the influence of Metropolitanate of Kiev in Kievan Rus.
[1] Eastern Orthodoxy was especially strong among the population of Rusyns, until the middle of 17th century when the Union of Uzhhorod (1646) was brought about in the Kingdom of Hungary.
On 25 September 1921, Archimandrite Gorazd was consecrated Bishop of Moravia and Silesia at the Cathedral of the Holy Archangel Michael in Belgrade, Yugoslavia, by Serbian Patriarch Dimitrije.
In 1939, the Nazi Germany annexed the remainder of the Czech lands into the Protectorate of Bohemia and Moravia and installed a pro-Nazi regime in the Slovak State.
In the same time, Hungary occupied the rest of Carpathian Rusynia and in 1941 Hungarian authorities deported bishop Vladimir Rajić to Serbia.